Dong-Sik Shin.

Post-Doctorate Researcher
University of California, Berkeley

Ph.D. Chemical Engineering, 2006
Seoul National University
M.S. Chemical Engineering, 2001
Seoul National University
B.S. Chemical Engineering, 1999
Seoul National University

dongss2(AT)berkeley.edu
Office Location: 497A Tan Hall
Office Telephone: 510-643-8340
Office Fax: 510-643-1228


My research area is solid phase peptide synthesis and the screening of biomolecules. On the basis of my experience, I joined the projects of solid phase biocatalysis and high throughput multizyme chip in the Clark lab.

i) Solid phase biocatalysis is facile to produce new chemical entities (NCEs) due to easy separation of product. NCEs can be produced variously and chemoselectively by successive enzyme reactions on the solid support.

ii) The main goal of high throughput multizyme chip project is the toxicity screening of metabolized products from NCEs. Co-working with Dordick group (RPI), prototype of toxicity screening system was successfully verified by combining MetaChip1 (multizyme chip) and DataChip2 (cell chip). We are expecting to open a new paradigm of in vitro toxicity test in a high throughput manner.

References
1. Lee M-Y, Park CB, Dordick JS, Clark DS (2005) Proc Natl Acad Sci USA 102: 983-987
2. Lee M-Y, Kumar RA, Sukumaran SM, Hogg MG, Clark DS, Dordick JS (2008) Proc Natl Acad Sci USA 105: 59-63